Systemic IL-12 Administration Alters Hepatic Dendritic Cell Stimulation Capabilities
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چکیده
منابع مشابه
Systemic IL-12 Administration Alters Hepatic Dendritic Cell Stimulation Capabilities
The liver is an immunologically unique organ containing tolerogenic dendritic cells (DC) that maintain an immunosuppressive microenvironment. Although systemic IL-12 administration can improve responses to tumors, the effects of IL-12-based treatments on DC, in particular hepatic DC, remain incompletely understood. In this study, we demonstrate systemic IL-12 administration induces a 2-3 fold i...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0033303